Polynucleotides Treatment Guide: What It Is, Areas We Treat & What to Expect
- AJM Aesthetics

- Jul 31
- 2 min read

Polynucleotides are an advanced regenerative injectable treatment designed to repair, rejuvenate and improve the quality of the skin from within. Rather than adding volume like dermal fillers, polynucleotides work by stimulating your body’s natural healing processes, encouraging collagen production, improving skin elasticity and boosting hydration. They are commonly used to treat the face, under-eye area, neck, décolletage and hands, helping to improve fine lines, skin texture and overall skin health. Mild redness, swelling, tenderness and small bumps at the injection sites are completely normal and will settle as the product begins to stimulate tissue regeneration. For the safest recovery and the best possible results, please follow the aftercare guide below.
What is Polynucleotides Treatment Guide: What It Is, Areas We Treat & What to Expect?
Polynucleotides are injectable skin-rejuvenation treatments used to support skin quality and overall skin health. They’re often chosen to improve texture, hydration and the appearance of fine lines, especially in areas where skin looks thin, tired or crepey.
Areas we treat
Face
Under-eyes
Neck
Décolletage
Hands
Step-by-step: what to expect
Consultation & suitability check (including under-eye assessment if relevant)
Treatment plan agreed (areas and course)
On the day: cleanse, prep and mark injection points
Treatment: injections placed across the chosen area
Aftercare advice
Review and plan next session
Aftercare
Avoid rubbing/massaging the area unless advised
Avoid strenuous exercise, alcohol and heat exposure for 24 hours
Avoid makeup on the treated area for the rest of the day (where possible)
SPF daily and gentle skincare
Results timeline
Early improvements may be noticed within 1–2 weeks
Skin quality typically improves progressively across the course
Best results are usually assessed after completing the recommended sessions
How many sessions will I need?
Most clients benefit from a course with maintenance tailored to their skin goals. We’ll confirm your plan during consultation.
Safety & suitability
Not suitable during pregnancy or breastfeeding
A full medical consultation is required
Temporary swelling, redness or bruising can occur
FAQs
Are polynucleotides good for under-eyes?
They can be a great option for suitable clients where the goal is improving skin quality in delicate areas. We’ll assess suitability first.
Is there downtime?
Most clients return to normal activities quickly, though mild swelling or small bumps can occur temporarily.
How long do results last?
Longevity varies by individual and treatment plan. Maintenance is usually recommended to keep results looking their best.
Ready to book?
If you’d like to improve skin quality with a bespoke plan, book a consultation with AJM Aesthetics in Exeter. We’ll assess your skin, talk through options, and recommend the most suitable course for your goals.





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